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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PXN
All Species:
24.55
Human Site:
S226
Identified Species:
45
UniProt:
P49023
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49023
NP_001074324.1
591
64533
S226
S
L
L
D
E
L
E
S
S
V
P
S
P
V
P
Chimpanzee
Pan troglodytes
XP_001159942
589
64154
S224
S
L
L
D
E
L
E
S
S
V
P
S
P
V
P
Rhesus Macaque
Macaca mulatta
XP_001085795
563
61555
S232
S
L
L
D
E
L
E
S
S
V
P
S
P
V
P
Dog
Lupus familis
XP_543425
664
72715
S237
S
L
L
D
E
L
E
S
S
V
P
S
P
V
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8VI36
591
64458
S226
S
L
L
D
E
L
E
S
S
V
P
S
P
V
P
Rat
Rattus norvegicus
Q66H76
586
64001
N217
Y
G
V
P
E
S
N
N
L
L
G
G
K
A
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P49024
559
61224
S227
S
L
L
D
E
L
E
S
S
V
P
S
P
V
P
Frog
Xenopus laevis
Q2TCH4
506
55983
T187
D
L
S
S
P
R
S
T
A
C
V
P
K
D
L
Zebra Danio
Brachydanio rerio
Q6P7E4
419
45574
S100
K
D
S
L
T
S
S
S
S
Q
P
K
Y
S
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523601
581
64668
D214
T
E
K
L
T
G
P
D
G
P
V
G
T
V
E
Honey Bee
Apis mellifera
XP_624308
559
62451
A211
K
E
L
D
D
L
M
A
S
L
S
E
F
K
P
Nematode Worm
Caenorhab. elegans
Q09476
413
46434
L94
I
Y
E
N
E
S
R
L
N
P
P
V
Y
S
R
Sea Urchin
Strong. purpuratus
XP_780574
695
76058
Q309
H
S
A
P
P
S
Q
Q
Q
H
Q
Q
P
M
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
92.5
83.1
N.A.
93.7
74.9
N.A.
N.A.
84.7
41.2
21.6
N.A.
43.1
43.3
33.8
43.4
Protein Similarity:
100
99.1
92.8
85.2
N.A.
95.7
78.3
N.A.
N.A.
88.4
54.3
36.5
N.A.
54.8
57
47
56.2
P-Site Identity:
100
100
100
100
N.A.
100
6.6
N.A.
N.A.
100
6.6
20
N.A.
6.6
33.3
13.3
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
26.6
N.A.
N.A.
100
20
20
N.A.
13.3
53.3
26.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
8
8
0
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
8
8
0
54
8
0
0
8
0
0
0
0
0
8
0
% D
% Glu:
0
16
8
0
62
0
47
0
0
0
0
8
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
8
% F
% Gly:
0
8
0
0
0
8
0
0
8
0
8
16
0
0
8
% G
% His:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
16
0
8
0
0
0
0
0
0
0
0
8
16
8
0
% K
% Leu:
0
54
54
16
0
54
0
8
8
16
0
0
0
0
8
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
0
0
8
0
% M
% Asn:
0
0
0
8
0
0
8
8
8
0
0
0
0
0
0
% N
% Pro:
0
0
0
16
16
0
8
0
0
16
62
8
54
0
54
% P
% Gln:
0
0
0
0
0
0
8
8
8
8
8
8
0
0
0
% Q
% Arg:
0
0
0
0
0
8
8
0
0
0
0
0
0
0
8
% R
% Ser:
47
8
16
8
0
31
16
54
62
0
8
47
0
16
8
% S
% Thr:
8
0
0
0
16
0
0
8
0
0
0
0
8
0
0
% T
% Val:
0
0
8
0
0
0
0
0
0
47
16
8
0
54
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
8
0
0
0
0
0
0
0
0
0
0
16
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _